Veterans Health Venture Studio is a cohort-based innovation initiative powered by a public–private collaboration among the Tampa VA Medical Center, the VHA Innovation Ecosystem, and Microsoft. The program is structured around three phases—Hackathon, Make-a-thon, and Accelerator—and builds a pipeline of impactful AI-powered health care innovations that address complex challenges within health care, while cultivating an ecosystem of VA and private sector innovators, researchers, and technology industry leaders.